u/LDNadminFB
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15points
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16points
Introduction to LDN (self.LowDoseNaltrexone) [pinned]
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2points
Low Dose Naltrexone for Healthspan: What Our Real-World Study Found (self.LowDoseNaltrexone)
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8points
Profile name mistake (self.LowDoseNaltrexone)
LDNadminFB
LDNadminFB
Finding your optimal dose (which may NOT be a higher dose like 4.5mg)...
At some point during the titration up process you may feel you were doing better on the previous dose. If you still feel that way after giving your system two weeks to adapt, then you may have found your optimal dose. Then skip a dose or two and drop back to the previous level. May occasionally want to test an increase to see if there are additional benefits, but consider finding your optimal dose whatever it is as a "win."
Higher and Lower Doses...
https://docs.google.com/document/d/1KykpLlg2CDVSD2D5J5cEZKfSo31t04orB0IgCuhXC-c/edit?usp=sharing
LDNadminFB
LDNadminFB
Morning and Other Dosing Times
https://docs.google.com/document/d/1aUi8UovaSAD2VO1Bc2O2I8PtfMPFbv5zsulRqyNDD9U/edit?usp=sharing
LDNadminFB
Dr. Kim - When LDN Crashes the System: Ultra-Low-Dose Strategies for MCAS, POTS, and the Hypersensitive Client…
Initial reactions often settle within two weeks, but if not or it's too difficult you may need to go to a lower dose like 0.5mg or even 0.1mg.
Higher and Lower Doses...
https://docs.google.com/document/d/1KykpLlg2CDVSD2D5J5cEZKfSo31t04orB0IgCuhXC-c/edit?usp=sharing
Most reports of filler/ingredient trouble are with Avicel (Microcrystaline cellulose/MCC/cellulose) even though it may be tolerated in other meds/supplements.
Avicel and Other Fillers...
https://docs.google.com/document/d/171pT-q4ND3_RbdioLBvl-uCXWIelKtW98AEnH07H2Fs/edit?usp=sharing
If the link doesn't work for you try signing into Google first
Symptoms During the First 3 to 6 Months...
https://docs.google.com/document/d/1nD2ODu6AYJfaIBLvTLq62O94u7-w38vjia-SPImvYeI/edit?usp=sharing
How Long to Notice Benefits from LDN?
https://docs.google.com/document/d/1txJRzIp7uK0XXeyqpcAoYRr_z179oAjRWbn2TGaKwiE/edit?usp=sharing
Success Stories from the LDN Chronic group on Facebook (group is now on Reddit and MeWe as LDN International)
- not sorted by condition, but document can be searched for mentions...
https://docs.google.com/document/d/1ruk5xYyOs5QnI04j5Ai2v1e5v9ioLfld-xuepb7EHT4/edit?usp=sharing
LDNadminFB
For some the filler is a problem -
Most reports of filler/ingredient trouble are with Avicel (Microcrystaline cellulose/MCC/cellulose) even though it may be tolerated in other meds/supplements.
Avicel and Other Fillers...
https://docs.google.com/document/d/171pT-q4ND3_RbdioLBvl-uCXWIelKtW98AEnH07H2Fs/edit?usp=sharing
If the link doesn't work for you try signing into Google first
Some with GI issues do better with a sublingual form -
Sublingual drops -- formulas vary but tend to be simpler/cleaner vs. other liquid versions. Example - Dickson's formula: Pure Naltrexone Powder, Water, Glycerol. Check your pharmacy's ingredients. Good for those with GI issues. Dose with the included dropper. If you are very sensitive in terms of GI issues ask your pharmacist how long you would need to hold the dose in your mouth to have it adequately absorbed before spitting out what's left so that less of the dose goes to your stomach. While holding if you have an irresistible urge to swallow tilt the head forward so the dose stays mainly in the mouth. Let us know what your pharmacist says.
Symptoms During the First 3 to 6 Months...
https://docs.google.com/document/d/1nD2ODu6AYJfaIBLvTLq62O94u7-w38vjia-SPImvYeI/edit?usp=sharing
Dr. Kim - When LDN Crashes the System: Ultra-Low-Dose Strategies for MCAS, POTS, and the Hypersensitive Client…
LDNadminFB
How Long to Notice Benefits from LDN?
https://docs.google.com/document/d/1txJRzIp7uK0XXeyqpcAoYRr_z179oAjRWbn2TGaKwiE/edit?usp=sharing
Researching Your Condition...
https://docs.google.com/document/d/1vEqNB4A8E1Oivdcr9UqJkjeiPk_zs3_1yx6f_gn9AZ8/edit?usp=sharing
LDNadminFB
Morning and Other Dosing Times
https://docs.google.com/document/d/1aUi8UovaSAD2VO1Bc2O2I8PtfMPFbv5zsulRqyNDD9U/edit?usp=sharing
LDNadminFB
Related -
Most reports of filler/ingredient trouble are with Avicel (Microcrystaline cellulose/MCC/cellulose) even though it may be tolerated in other meds/supplements.
Avicel and Other Fillers...
https://docs.google.com/document/d/171pT-q4ND3_RbdioLBvl-uCXWIelKtW98AEnH07H2Fs/edit?usp=sharing
If the link doesn't work for you try signing into Google first
LDNadminFB
Related -
Long Term Use...
https://docs.google.com/document/d/1Ye36cI50kAXk4D-FPjrK64mNuOUWDtr4DwAevGyr1uI/edit?usp=sharing
Depression and Psychiatric links …
https://docs.google.com/document/d/1IjrfSGtst0jszho5sxFOOhC5ukgGck_94xFJlQo2Dnc/edit?usp=sharing
LDNadminFB
The dose skip test may be a good idea. Related -
Long Term Use...
https://docs.google.com/document/d/1Ye36cI50kAXk4D-FPjrK64mNuOUWDtr4DwAevGyr1uI/edit?usp=sharing
LDNadminFB
The patient flyer from regular dose Naltrexone warns about taking Naltrexone when the patient has been on regular opioid dosing. Up to a two week gap is required before starting.
"To prevent occurrence of precipitated withdrawal in patients dependent on opioids, or exacerbation of a pre-existing subclinical withdrawal syndrome, opioid-dependent patients, including those being treated for alcohol dependence, should be opioid-free (including tramadol) before starting REVIA treatment. An opioid-free interval of a minimum of 7 to 10 days is recommended for patients previously dependent on shortacting opioids. Patients transitioning from buprenorphine or methadone may be vulnerable to precipitation of withdrawal symptoms for as long as two weeks."
https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018932s017lbl.pdf
As a safety measure before starting a naloxone (N.B. NOT Naltrexone) challenge test is administered. If interested this would be a relatively low risk way of determining your risk of precipitated withdrawal when using LDN.
LDNadminFB
Wow! Thank you so much! That was a total duh brain mis-fire on my part jumbling the profile name. All fixed now. Bravo for spotting that!!!
LDNadminFB
You're very welcome and we appreciate the appreciation! :)
LDNadminFB
Using Naltrexone for conditions other than addiction is an "off-label" use. This is common practice that your doctor should be familiar with:
https://www.health.harvard.edu/blog/what-off-label-use-of-a-drug-really-is-and-why-you-need-to-know-about-it-201509048225
More info:
Medical Records...
https://docs.google.com/document/d/1oTfUtaazXliKV4-D9yXwHR6wvs5PLrEPKroLmG9Ls8U/edit?usp=sharing
LDNadminFB
Terrific! Thanks for reporting :)
LDNadminFB
Success Stories from the LDN Chronic group on Facebook (group is now on Reddit and MeWe as LDN International)
- not sorted by condition, but document can be searched for mentions...
https://docs.google.com/document/d/1ruk5xYyOs5QnI04j5Ai2v1e5v9ioLfld-xuepb7EHT4/edit?usp=sharing
Pain and related info...
https://docs.google.com/document/d/1cf8ZQaSveZftOvKCND64Eykri065g5qg7bmZQCbbLVo/edit?usp=sharing
Taking it with food may help with nausea. Filler is an issue for some -
Most reports of filler/ingredient trouble are with Avicel (Microcrystaline cellulose/MCC/cellulose) even though it may be tolerated in other meds/supplements.
Avicel and Other Fillers...
https://docs.google.com/document/d/171pT-q4ND3_RbdioLBvl-uCXWIelKtW98AEnH07H2Fs/edit?usp=sharing
If the link doesn't work for you try signing into Google first
LDNadminFB
Finding your optimal dose (which may NOT be a higher dose like 4.5mg)...
At some point during the titration up process you may feel you were doing better on the previous dose. If you still feel that way after giving your system two weeks to adapt, then you may have found your optimal dose. Then skip a dose or two and drop back to the previous level. May occasionally want to test an increase to see if there are additional benefits, but consider finding your optimal dose whatever it is as a "win."
Higher and Lower Doses...
https://docs.google.com/document/d/1KykpLlg2CDVSD2D5J5cEZKfSo31t04orB0IgCuhXC-c/edit?usp=sharing
LDNadminFB
It would be an experiment, but I would bet tempted to try a slight reduction in your thyroid meds and see what you notice. LDN can improve thyroid function and it may be that the way you are feeling is a better indicator than the tests.
Some have to start LDN with a lower than typical dose.
Higher and Lower Doses...
https://docs.google.com/document/d/1KykpLlg2CDVSD2D5J5cEZKfSo31t04orB0IgCuhXC-c/edit?usp=sharing
Dose Dilution and Adjusting...
https://docs.google.com/document/d/1-B2iX9uFDSUI7mVfiD4VR2FksxbSG2YELjQHZ_913do/edit?usp=sharing
LDNadminFB
Skipping a Dose as a Test...
https://docs.google.com/document/d/1wn_fixJuQEg8V5SV2mlh7suK0AJoorSjTbVUTnLDHnQ/edit?usp=sharing
Finding your optimal dose (which may NOT be a higher dose like 4.5mg)...
At some point during the titration up process you may feel you were doing better on the previous dose. If you still feel that way after giving your system two weeks to adapt, then you may have found your optimal dose. Then skip a dose or two and drop back to the previous level. May occasionally want to test an increase to see if there are additional benefits, but consider finding your optimal dose whatever it is as a "win."
Higher and Lower Doses...
https://docs.google.com/document/d/1KykpLlg2CDVSD2D5J5cEZKfSo31t04orB0IgCuhXC-c/edit?usp=sharing
LDNadminFB
If they are useful roll with it lol. Otherwise maybe try morning dosing.
Morning and Other Dosing Times
https://docs.google.com/document/d/1aUi8UovaSAD2VO1Bc2O2I8PtfMPFbv5zsulRqyNDD9U/edit?usp=sharing
You could keep slowly titrating up as in at least 2 weeks between increases.
Finding your optimal dose (which may NOT be a higher dose like 4.5mg)...
At some point during the titration up process you may feel you were doing better on the previous dose. If you still feel that way after giving your system two weeks to adapt, then you may have found your optimal dose. Then skip a dose or two and drop back to the previous level. May occasionally want to test an increase to see if there are additional benefits, but consider finding your optimal dose whatever it is as a "win."
Higher and Lower Doses...
https://docs.google.com/document/d/1KykpLlg2CDVSD2D5J5cEZKfSo31t04orB0IgCuhXC-c/edit?usp=sharing