Lady Gaga's fiancé, Michael Polansky, runs a company that takes discarded human skin (mostly from plastic surgery), keeps it alive for a month so they can test cosmetics on it

Polansky just did an interview with TechCrunch, which is where I learned about all this for the first time!

From the company's website
From the company's website
From TechCrunch's interview with Polansky
From TechCrunch's interview with Polansky
Lady Gaga sits on the Board of Directors for the company
Lady Gaga sits on the Board of Directors for the company
Lady Gaga's mom was the one who introduced the two of them!
Lady Gaga's mom was the one who introduced the two of them!

271 comments · 96% upvoted · source · other discussions

comments

GuaranteeNo27

I'd take this over animal testing

BrownSugarBare

Honestly, this is genius. No one harmed, it's technically bio waste anyways. 

The only concern would be ensuring DNA and identity is not housed anywhere. Otherwise, this works for me. 

Gayfetus [OP]

From the article:

Asked about the donors’ privacy, he says that every sample arrives already de-identified — stripped upstream by the supplying organizations of names, contact information and other direct identifiers.

I assume they don't collect the DNA profiles, and after the skin dies it's probably disposed of via incineration.

RedSunsetSukuna85

I don’t see the issue unless they don’t try to help lower the medical bills of the donated and the choice to share that. I would even be okay with them in keeping my donated material away from the Israeli military because I didn’t sign up to be a donor to help Israel observe dead bodies being blown up. (This was a recent scandal involving USC sharing catheters with the Israeli military).

load 3 more replies →

Angryduckling-01

And unlike animals this isn’t just similar to humans this is from an actual human

NSASpyVan

There is an ethics class debate about this involving a woman named Henrietta Lacks.

She had cells taken from her body without being asked. They were used to create the first immortal human cells, called HeLa cells. These concepts go into things like informed consent.

load 24 more replies →

andorgyny

Agreed, unless the skin is unethically sourced.

um_-_no

Yes that was my concern! My instinct is this sounds great, but if they're scalping prisoners or running exploitative practises to get skin from under privileged people then uh oh

It seems unlikely to me, but fucking hell in this world, idek anymore

runner64

Tbh I don’t think they’d need to, people are getting tummy tucks and breast lifts constantly. 

Pale-Proposal8046

I was gonna say lol there's not exactly a shortage of people voluntarily removing their skin.

hellolovely1

Especially now that we have Ozempic.

MCRV11

Super morbidly obese people who manage to get down to healthy weights and want excess skin removed too.

There's usually a LOT of excess skin in those situations

citizen42069101

Luckily in la theres plenty of people carving chunks off. Surprised no ones started a soap business with the fat.

ReeveStodgers

There is one guy who did just that, but his company seems like a cult. They're always chanting about "Robert Paulson."

cassssk

Don’t give the chucklefucks on Mc Bees’ Dynasty any more ideas to “save the farm” lol

load 1 more replies →

GlassPomoerium

Fun fact (not): there’s a cosmetic injectable made of organ donor fat and 99% of donors don’t even know that’s a possibility for their remains 🙃 Oh and it’s of course sold for profit! And you can’t always opt out of it anyway!

MsBit_Commit

Here’s the thing about organ donation: there is a LOT of you. Not all of your organs will be in perfect condition to save a heart patient or lung patient. There’s still 100+ pounds of Person to deal with. On me, that’s gonna be a lot of fat. God knows nobody is gonna want my eyeballs, and I’m asthmatic so probably not my lungs, either. It might as well go somewhere.

GlassPomoerium

For sure it’s very zero-waste lol. If donors are informed of it ahead of time, sure. But most people don’t know their fat can be sold and used for unnecessary cosmetic procedures, a few people surveyed in the article actually removed their names from the donor registry. But I’m sure some Kardashian fans would be like

https://giphy.com/gifs/WpalL2ofcbok7kHRJm

MsBit_Commit

I think informed consent is honestly more important in general- right now, you tick a box and you’re an organ donor. I have no idea how any of my parts will be used, and maybe we should broaden that conversation.

bloodyturtle

Helping someone looked snatched from beyond the grave sounds nice actually

[deleted]

[deleted]

pegmatitic

I hate this timeline

SarryK

flair checks out :(

SlinkyRaccoons
badashbabe

The tragic irony continues to unfold in the most horrifying ways, doesn’t it

applesandbananananan

Dear god

itmustbeniiiiice

Oh god.

load 3 more replies →

load 1 more replies →

kingxfmischief

Honestly this is the problem with a lot of human based testing over animal testing. Like yes we should move away from animal testing where we can, but a lot of human based testing is unethical in one way or another. 

wistfulwhileyoutwerk

That’s a valid concern, but the fault for that would lie with the sourcing company and not Outer-Bio.

load 3 more replies →

afarensiis

Yeah it kind of sounds terrifying, but much preferable to many other alternatives when you think about it

firewontquell

As a scientist, a patch of skin cannot replace full body models. A patch of skin doesn’t have an immune system or nervous system or circulatory system or any other “system” that is required to really see if there are problems with a drug or cosmetic or anything else sold or given to consumers.

NSASpyVan
Effective-Bus

SAY IT LOUDER!!!

This is brilliant! I hope more employ it. There is no reason animal testing should be conducted on animals, especially for cosmetics and hair products.

cubdawg

This is the exact point! Same as organoid models. Some things don’t need live animal models, and the NIH is finally agreeing.

load 12 more replies →

hotgossyo

this is sketchy. as someone who works in legal for global clinical research trials, the fact that he claims the samples are deidentified is wildly incorrect. he might not be able to trace the sample to the surgery center it came from, but there is biological data that could be obtained from tissue, which could identify someone. then he is training an AI model…jfc this is actually terrifying.

andorgyny

I need to know where exactly they are getting the skin from. Too many unethical ways to build a human skin bank (see: israel's skin bank).

They claim it's mostly from like unused skin tissue from plastic surgery but idk that I trust any tech startup whose co-founder has ties to peter thiel (or any tech startup at all lbr).

Culinary_Fruit_Salad
andorgyny

Exactly. I have my concerns and they aren't unfounded.

[deleted]

[deleted]

Big-Snow-1937

It’s relevant here because she’s listed as a member of the Board of his company on one of the slides. 

Culinary_Fruit_Salad

that's disgusting. thank you for that information

Gayfetus [OP]

Per the article:

So Outer Biosciences took a different approach. Instead of engineering a synthetic organ, the company sources human skin that would otherwise be discarded after surgery – mostly plastic surgery – through what it describes as vetted non-profit and commercial biobanks and brokers operating under “institutional review board oversight and documented donor consent,” principally the National Disease Research Interchange and the Cooperative Human Tissue Network. (Both outfits receive federal funding from the NIH and the National Cancer Institute without being federally operated.)

I'm not familiar enough with those systems to say that they have enough safeguards against possible exploitation somewhere in the chain.

canththinkofanything

IRB oversight is what you need before any clinical trial involving humans. I’ve run several clinical trials but with much much lower stakes interventions! IRB is the first step before you get things up and running, and is there to make sure you’re following rules and are properly protecting human subjects. They take that very seriously- I’ve spent a literal year going around with IRB to try and get a project started.

Before that though, the NIH has a lot of their own rules and regulations that are implemented to keep people safe. To even get a grant you need to show exactly how you’re going to do the research and there may be recommendations to change things if thought necessary. Big grants are chosen by peers and a slightly convoluted (imo) ranking system.

After being chosen for a grant, they will have a NIH program officer that is assigned to the project who is responsible for monitoring their progress and making sure everything is in order. Depending on who gives funding and the working style of the PO, I’ve had occasional check ins when things are happening, with emails between, to weekly meetings.

Now, that doesn’t automatically mean everything is all peachy and on the up and up - there’s self reporting that you’d need to do, and while there are audits, they’re random and may not catch anything. But that’s like a worst case scenario and I’ve never known anyone to be deceitful or improper with this funding.

It’s an enormous privilege to get a large NIH grant, and those I’ve worked with all take the responsibility very seriously. I work in public health research by the way. I also write this half dazed after I woke up from a nap, and this is very much not my area of work, so anyone please correct me if I’m wrong or missed something!

[deleted]

load 1 more replies →

MysteriousHat3705

the first thing that came to my head

https://giphy.com/gifs/fVVfz6PH1qmRp7cxql

dr_delphee

100% me too. I scrolled looking for this, because as soon as I read the headline I thought:

"MOISTURIZE ME!"

unique_plastique

It’s been feeling like there’s an agenda when people present him as gaga’s fiancé when that has nothing to do with his professional career. It gives more context to give context to his business affiliations instead of a personal.

That being said, Polansky is a former principal at Peter Thiel’s company Founder’s Fund

Puzzled-Ticket-4811

I think it's important context to suss out whether to like Lady Gaga any more as a person. Most of the time I agree who a celebrity is married to usually isn't important. The fact he's affiliated with Peter Thiel and she's fine with that speaks volumes about her character.

unique_plastique

I already know what Miss “I fucking love you Israel” is about

Gayfetus [OP]

I thought it was relevant in this case because Gaga has a personal and professional interest in cosmetics, even before she met Polansky. She also sits on the board of directors of the company. So it was one of those, "huh, it actually makes sense that this is what he does."

The Peter Thiel association is super sketchy. Although, I'm not sure I'd trust a venture capitalist even if they aren't associated with Thiel.

kristaycreme

Nothing will make me like this Peter Thiel VC bro.

Gayfetus [OP]

I think this is neat! Not as neat: Lady Gaga's past support for Israel and her continued silence about the genocide in Gaza.

BrownSugarBare

Oh faaaaack that. 

FREE PALESTINE 

TheEldestNugget

Israel has also been known to harvest organs, including skin, from detained Palestinians.

Xanto97

Technically not just Palestinians.

But it’s uh, still quite bad.

“Channel 2 TV reported that in the 1990s, specialists at Abu Kabir harvested skin, corneas, heart valves and bones from the bodies of Israeli soldiers, Israeli citizens, Palestinians and foreign workers, often without permission from relatives.
The Israeli military confirmed to the programme that the practice took place, but added: "This activity ended a decade ago and does not happen any longer."
Hiss said: "We started to harvest corneas ... whatever was done was highly informal. No permission was asked from the family."
However, there was no evidence that Israel had killed Palestinians to take their organs, as the Swedish paper reported. Aftonbladet quoted Palestinians as saying young men from the West Bank and Gaza Strip had been seized by the Israeli forces and their bodies returned to their families with missing organs. “

raddoubleoh

EXCUSE ME?! SKIN?!?

SARB033

Israel has the largest skin bank on the planet. Only 14% of Israelis are signed up as organ donors, though. Nobody seems to know where the skin came from. Real head scratcher.

raddoubleoh

Bruh, this is BEYOND diabolical, what the hell...

evthrowawayverysad

I feel like, geographically speaking, israel would be like 3 or 4 highway exits beyond diabolical.

heartisallwehave

First thing I thought of.

load 2 more replies →

shgrdrbr

thank you for noting this as well. this must be amplified.

ChickenConstant9855
Acheloma

It should be clarified that this is from deceased persons and (according to this source, but ig you cant prove anything) ended in the 1990s, they didnt pull a "wake up in a bathtub full of ice missing a kidney".

Its still unethical, but not as horrific as I expected baed on the previous comments.

load 4 more replies →

wingedcoyote

What an interesting time capsule, apparently in 2014 Gaga was "the first big-name star to perform in Israel in the wake of the country’s ongoing conflict with Palestine." Right now they want you to think the "war" started in 2023, I guess back then they were also pretending that it had just started.

GaylicBread

She also used AI in her Mayhem merch

load 16 more replies →

CuddlyClubCEO

idk man mega rich tech nerd meets her at met gala and starts writing and producing her music with no previous experience. is now using her to pump his tech company. im skeptical 🤷🏻‍♀️

kristaycreme

Someone on another sub posted a list of all of Gaga’s projects in the last 3 or so years and his name is EVERYWHERE. Did you know he’s a composer? lol

Ok-Airport-6058

Better than poor rabbits and dogs, right? 🤷‍♂️

spirithousing

and our little rat buddies too! 🐀

Merryprankstress

Rats, rabbits, mice, chimpanzees, dogs, other primates, cats etc etc

browsinbowser

No, if theres even a chance it’s unethical to humans than its far worse..This guy used to be a founder at one of Peter Thiels companies. And the de-stripping identity makes it a bit suspicious/susceptible to bad body brokers.

heartisallwehave

How do you follow the chain back to source and guarantee it’s ethical if the identity has been stripped?

lacey_nightie

realistically, knowimg american big pharma, it's probably going to be palestianian and prisoner skin unless the company can provide verifiable receipts on where the skin comes from and if it was ethically taken

load 1 more replies →

vonsnape

is. . . is this good?

Littlebotweak

It’s as good as the systems in place that guarantee ethics…..

vonsnape

speaking as a godless european communist, comrade, i agree

aikidharm

As a godless American communist, I also agree.

vonsnape

inshallah comrade, we will rise together

MrYellowFancyPants

I think its better than testing on animals like a lot of companies do

avidbather

It's pretty cool, yeah

Maya_TheB

Possibly the solution to end animal testing so honestly yeah kinda !

load 1 more replies →

BonJovicus

As a researcher, this is an interesting solution for cosmetics testing. I will always emphasize that animal models are and will continue to be important for basic science research: save animal use for genuinely life changing projects such as testing cancer drugs in a setting that is heavily regulated such as an academic medical center.

That said we should always be concerned with the ethics and marketing of companies like this one. How they are obtaining the tissue is one thing, which is a huge issue right now because of recent scandals. Do patients know where their tissue is going? The article hints at existing mechanisms, but there are already problems with those existing mechanisms. Lots of tissue ends up in the hands of shady vendors and moreover patients are unaware exactly towards what their biomaterial is going towards.

Puzzled-Ticket-4811

Katy Perry was rightfully clowned on for being out of touch, and I think it's Lady Gaga's turn for shacking up with a Peter Thiel affiliated techbro venture capitalist. My patience is running thin for all these 'love will save the world' types who have no concern to being fascist adjacent like this. FYGM in action.

BarracudaNo9507
BrieflyReanimated

Interesting how this has been reposted without the mention of the company’s AI use in the title.

Has the other post been deleted because I can’t find it? Consensus was a lot less optimistic of the post I saw last night about this.

The man has worked with Peter Thiel

CandidateHefty329

That's awesome!

ClintBarton616

I feel like I should be able to sell my extra skin (dystopian) instead of these guys just getting to fish it out of the trash.

If we're doing horror capitalism let's just commit

catseyeon

My claim to fame is I used to work in the same building, on the same floor as Outer Biosciences! lol

Gayfetus [OP]

So you've got... skin in the game!

https://giphy.com/gifs/Vj97qNut6WDHa

Illustrious_Bed_3772

There needs to be full transparency over where the skin is coming from. As in: locations imported.
Israel has the largest skin bank in the world - and you know why.

SL_1183

Disgustingly cool, but my bullshit-o-meter is going off.

BubbleCrum

Gross. Cool.

Ambitious-Chest2061
Crochet_Sparkles

Anyone else think this feels a little Theranos-y?

trekbek

I'm pretty sure the technology of temporarily preserving human skin is relatively well-established.

load 3 more replies →

Reasonable-Cut-9090

I do find interesting the major difference between threads reactions on this story when "AI" is in the title or not, granted this post gives a lot more context too

load 88 more replies →